A Rational Adoption of the High Sensitive Assay for Cardiac Troponin I in Diagnostic Routine
نویسندگان
چکیده
منابع مشابه
A Rational Adoption of the High Sensitive Assay for Cardiac Troponin I in Diagnostic Routine
We describe the adoption of high sensitive troponin I (hsTnI) in clinical practice in two hospital settings in Italy. Samples from 426 consecutive patients (mean age 68.8 ± 17.0) admitted to the Emergency Department with a suspected acute coronary syndrome (ACS) have been tested at admittance and after 3 and 6 hours by contemporary TnI and hsTnI. Results have been compared to the final clinical...
متن کاملHighly sensitive cardiac troponin I assay leads to lowered specificity.
I read with great interest the article of Kavsak et al. (1 ) on the utility of a next-generation high-sensitivity Beckman Coulter cardiac troponin I (cTnI) assay with a 20% CV at 2.95 ng/L. This approach demonstrated a higher diagnostic sensitivity (81% vs 62%) for myocardial injury with a changing pattern of cTnI values, compared with the AccuTnI assay cleared by the US Food and Drug Administr...
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Cardiac troponin is the preferred biomarker for the diagnosis of acute myocardial infarction (AMI). The recent development of a high-sensitive cardiac troponin T (hs-cTnT) assay permits detection of very low levels of cTnT. Using the hs-cTnT assay improves the overall diagnostic accuracy in patients with suspected AMI, while a negative result also has a high negative predictive value. The gain ...
متن کاملAnalytical performance of the i-STAT cardiac troponin I assay.
BACKGROUND This study determines the analytical characteristics of the i-STAT cardiac troponin I assay (cTnI; i-STAT, Princeton, NJ), a 10-min POC assay, designed to be performed at the bedside. METHODS Three different hospitals participated in a patient specimen and analytical validation study (n=186) for the i-STAT cTnI assay carried out in real time. A total of 186 whole blood specimens (l...
متن کاملProspective evaluation of the prognostic implications of improved assay performance with a sensitive assay for cardiac troponin I.
OBJECTIVES The purpose of this study was to investigate the prognostic implications of low-level increases in cardiac troponin I (cTnI) using a current-generation sensitive assay in patients with suspected acute coronary syndrome (ACS). BACKGROUND Recent enhancements in troponin assays have enabled resolution of the 99th percentile reference limit at progressively lower concentrations. Howeve...
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ژورنال
عنوان ژورنال: Disease Markers
سال: 2017
ISSN: 0278-0240,1875-8630
DOI: 10.1155/2017/4523096